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EMS Research

LITES PAIN Study

Linking Investigators in Trauma and Emergency Services (LITES) Prehospital Analgensia INtervention Trial (PAIN)

 

The LITES PAIN trial is a double-blinded study comparing fentanyl and pain-dose ketamine for trauma patients with compensated shock. While paramedics have already been using fentanyl and/or ketamine for several years in our EMS system, determination on which drug has mostly been left to the paramedic's clinical judgement or protocol; there are very few published studies comparing these drugs. 

  • The study kit contains two pre-filled, compounded syringes with either fentanyl or ketamine.
  • Dosage is standardized weight-based (1ml per 10kg) from either the Ketamine 25mg/10 ml (2.5 mg/ml) or Fentanyl 100  mcg/10 ml (10 mg/ml) syringes.
    • For example, a 70 kg patient will receive 7 ml from a blinded syringe yielding 17.5 mg of ketamine or 75 mcg of fentanyl
  • Paramedics may give two doses of the blinded drug and then go back to their routine protocol if pain continues

Please speak with trauma nurses and staff if the patient was administered the LITES PAIN study drug. 
Paramedics must hand-off the package envelope to the trauma nurse however they will follow their agency policy to dispose of the syringe; our EDTC team should not accept any syringes—just the package.

LITES SOAR Scorecard

More information on the LITES PAIN Study

Contact the MCW research team (Dr. Colella and Hannah Kovacevich) with any questions: [email protected].

 

Study Team

Dr. M. Riccardo Colella, DO,
MPH, FACEP Princible Investigator

Dr. Ben Weston, MD, MPH,
Co-Investigator

Hannah Kovacevich, MS,
Research Coordinator

Omar Davila, MPH,
Research Coordinator

Dan Pojar, BSEMS, FP-C, NRP,
EMS Division Director

Pedi-PART Study 

Pediatric (Pedi) Prehospital Airway Resuscitation Trial (PART)

The Pedi-PART study is designed to determine the best strategy to restore or maintain breathing in children.

There are three methods that EMS personnel currently use to maintain/restore breathing in children:

  • Bag valve mask ventilation (BVM): paramedics place a tight-fitting mask on top of the face and squeeze oxygen in through the mouth and nose and into the lungs.
  • Endotracheal intubation (ETI): paramedics place a plastic tube down the throat through the voice box and squeeze oxygen into the windpipe and lungs.
  • Supraglottic airway insertion (SGA): paramedics place a special tube in the mouth and down the throat above the voice box and squeeze oxygen into the windpipe and lungs.

In this study, we will determine which method works best for child survival by comparing the 3 methods that are used every day by emergency medical providers to manage airways and support breathing.

Participating EMS agencies will be assigned to use a different method each day. This will allow researchers to compare the effectiveness of each method. If the assigned method is unsuccessful then EMS may rescue with any other airway method.

More information on Pedi-PART Study

 

Study Team

Dr. M. Riccardo Colella, DO,
MPH, FACEP Princible Investigator Chief,
MCW Division of EMS Medicine

Dr. Ben Weston, MD, MPH,
Co-Investigator
EMS Medical Director
MCW Division of EMS Medicine

Wendy-Jo Wendt, MD
Co-Investigator
Assistant Professor of Pediatrics

Hannah Kovacevich, MS,
MCW Research Coordinator

Omar Davila, MPH,
MCW Research Coordinator

Dan Pojar, BSEMS, FP-C, NRP,
OEM EMS Division Director

Pedi-DOSE Study

Pediatric (Pedi) Dose Optimization for Seizures in EMS (DOSE)

 

Dr. Lorin Browne and Dr. Ben Weston of the Medical College of Wisconsin, Study Investigators for The Pediatric Dose Optimization for Seizures in Emergency Medical Services (PediDOSE) study, are trying to improve seizure outcomes in children by equipping paramedics to quickly give the right anti-seizure medication dose. Because it is a time-sensitive condition, when Milwaukee County EMS transports a child, they will get enrolled before parent/guardian permission can be sought. 

More Information on Pedi-DOSE Study 

MILWAUKEE COUNTY OFFICE OF EMERGENCY MANAGEMENT

633 W. Wisconsin Ave., Suite 700 
Milwaukee, WI 53203 

821 W. State St., Room 305
Milwaukee, WI 53233

24/7 number: (414) 257-4709

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