Emergency Management
 

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EMS Research

LITES PAIN Study

 

The LITES PAIN trial is a double-blinded study comparing fentanyl and pain-dose ketamine for trauma patients with compensated shock. While paramedics have already been using fentanyl and/or ketamine for several years in our EMS system, determination on which drug has mostly been left to the paramedic's clinical judgement or protocol; there are very few published studies comparing these drugs. 

  • The study kit contains two pre-filled, compounded syringes with either fentanyl or ketamine.
  • Dosage is standardized weight-based (1ml per 10kg) from either the Ketamine 25mg/10 ml (2.5 mg/ml) or Fentanyl 100  mcg/10 ml (10 mg/ml) syringes.
    • For example, a 70 kg patient will receive 7 ml from a blinded syringe yielding 17.5 mg of ketamine or 75 mcg of fentanyl
  • Paramedics may give two doses of the blinded drug and then go back to their routine protocol if pain continues

Please speak with trauma nurses and staff if the patient was administered the LITES PAIN study drug. 
Paramedics must hand-off the package envelope to the trauma nurse however they will follow their agency policy to dispose of the syringe; our EDTC team should not accept any syringes—just the package.

More information on the LITES PAIN Study
Contact the MCW research team with any questions: Dr. Colella and Hannah Kovacevich. 

 

Study Team

Pedi-PART Study    

The Pedi-PART study is designed to determine the best strategy to restore or maintain breathing in children.

There are three methods that EMS personnel currently use to maintain/restore breathing in children:

  • Bag valve mask ventilation (BVM): paramedics place a tight-fitting mask on top of the face and squeeze oxygen in through the mouth and nose and into the lungs.
  • Endotracheal intubation (ETI): paramedics place a plastic tube down the throat through the voice box and squeeze oxygen into the windpipe and lungs.
  • Supraglottic airway insertion (SGA): paramedics place a special tube in the mouth and down the throat above the voice box and squeeze oxygen into the windpipe and lungs.

In this study, we will determine which method works best for child survival by comparing the 3 methods that are used every day by emergency medical providers to manage airways and support breathing.

Participating EMS agencies will be assigned to use a different method each day. This will allow researchers to compare the effectiveness of each method. If the assigned method is unsuccessful then EMS may rescue with any other airway method.

More information on Pedi-PART Study

 

Study Team

 

 

MILWAUKEE COUNTY OFFICE OF EMERGENCY MANAGEMENT

633 W. Wisconsin Ave., Suite 700 
Milwaukee, WI 53203 

821 W. State St., Room 305
Milwaukee, WI 53233

24/7 number: (414) 257-4709

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